After Twin Peaks: Fire Walk with Me, David Lynch took his longest break between feature films. After a five-year pause, he released the neo-noir psychological horror film Lost Highway.
Partly inspired by the O.J. Simpson murder trial, the film is about a musician (Bill Pullman) who is convicted of murdering his wife (Patricia Arquette). While in prison, he suffers a breakdown and wakes up the next morning as a different person — a young mechanic played by Balthazar Getty. The confused authorities release the man, unsure of how we got there or what happened to the musician.
The movie then follows the mechanic as he gets entangled with a local gangster (Robert Loggia) and the man’s mistress (Arquette, again).